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This is the first game breaking bug that I encountered in Cyberpunk 2077.
For some unknown reason, the mouse scroll suddenly can’t be used to choose the dialogue options. All it does is switch the weapons.
Had to reload my previous save file to make it working back to normal.
source
I have exactly the same issue and its game breaking
yep same here
Happens to me as well, and I posted about it here:
https://forums.cdprojektred.com/index.php?threads/cant-choose-non-default-dialogue-options.11061842/
same here. 1.06 patched.
This just happened to me. I closed the game and reloaded. Annoying.